Jordan Montenegro

Publications

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Preprint2024
Amoebanator: Early Risk Triage with Calibration, Decision Curves, and Transparent Thresholds
J. Montenegro, Collaborators
clinical MLcalibrationdecision curvesexplainability
Abstract

We present a lightweight, well-documented clinical ML prototype that emphasizes calibrated risk, transparent thresholds via net benefit, and a reproducibility stack (model card, dataset card, and interactive demo).

Key contributions
  • Conformal-style safety control of false negatives during threshold selection
  • Decision-curve driven tuning for pragmatic operating points
  • Full reproducibility: interactive demo, model card, dataset card
Preprint2025
Montenegro’s Medium: Low-cost Culture Formulation Achieving 3–5× Growth for Naegleria fowleri
J. Montenegro
growth medialow-costlab methods
Abstract

A practical formulation and workflow that increases growth yield 3–5× while reducing consumable cost, enabling broader access to experimental work.

Key contributions
  • 3–5× growth in bench tests vs. baseline
  • Cost-aware formulation and sourcing notes
  • Reproducible protocol with QC checkpoints
Preprint2025
Organelle-Target Discovery: Drug Response Signatures and Mitochondrial Dysfunction Assays
J. Montenegro, Team
assayssignaturesmitochondria
Abstract

Exploration of organelle-level drug response with bench assays and analysis pipelines to surface candidate targets.

Key contributions
  • Assay design and QC for organelle-level readouts
  • Signature extraction pipeline with clear documentation
  • Hypothesis-generating leads for follow-up experiments